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Masatomo Miura Selected Research

Cytochrome P-450 CYP3A

1/2019Influence of CYP3A4/5 and ABC transporter polymorphisms on lenvatinib plasma trough concentrations in Japanese patients with thyroid cancer.
5/2018Effects of polymorphisms in NR1I2, CYP3A4, and ABC transporters on the steady-state plasma trough concentrations of bosutinib in Japanese patient with chronic myeloid leukemia.
5/2018Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitial fibrosis and long-term graft function in kidney transplant recipients.
11/2017Quantification of the steady-state plasma concentrations of clozapine and N-desmethylclozapine in Japanese patients with schizophrenia using a novel HPLC method and the effects of CYPs and ABC transporters polymorphisms.
7/2016Effects of CYP3A5 polymorphism on the pharmacokinetics of a once-daily modified-release tacrolimus formulation and acute kidney injury in hematopoietic stem cell transplantation.
9/2015Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease.
7/2015Relationship Among Gefitinib Exposure, Polymorphisms of Its Metabolizing Enzymes and Transporters, and Side Effects in Japanese Patients With Non-Small-Cell Lung Cancer.
1/2015Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation.
1/2015Effects of CYP3A5 polymorphism and the tacrolimus 12 h concentration on tacrolimus-induced acute renal dysfunction in patients with lupus nephritis.
11/2010Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia.
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Masatomo Miura Research Topics

Disease

20BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2022 - 11/2010
8Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2021 - 02/2014
8Neoplasms (Cancer)
04/2020 - 10/2009
8Body Weight (Weight, Body)
11/2017 - 10/2007
6Diarrhea
10/2021 - 10/2007
6Breast Neoplasms (Breast Cancer)
01/2021 - 10/2008
5Esophageal Neoplasms (Esophageal Cancer)
01/2022 - 10/2009
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
10/2021 - 05/2012
5Philadelphia Chromosome
10/2021 - 01/2011
5Multiple Myeloma
05/2019 - 08/2014
3Thyroid Neoplasms (Thyroid Cancer)
05/2022 - 01/2019
3Infections
11/2019 - 11/2007
3Renal Cell Carcinoma (Grawitz Tumor)
05/2018 - 01/2017
3Fibrosis (Cirrhosis)
05/2018 - 01/2011
3Squamous Cell Neoplasms (Squamous Cell Cancer)
03/2013 - 07/2011
2Schizophrenia (Dementia Praecox)
10/2021 - 11/2017
2Leukemia
08/2021 - 04/2012
2Esophageal Squamous Cell Carcinoma
01/2021 - 01/2012
2Stroke (Strokes)
01/2021 - 12/2017
2Hyperlipidemias (Hyperlipidemia)
06/2020 - 10/2007
2Colorectal Neoplasms (Colorectal Cancer)
04/2020 - 12/2014
2Ischemic Stroke
11/2019 - 12/2010
2Proteinuria
03/2019 - 01/2019
2Hypertension (High Blood Pressure)
03/2019 - 01/2019
2Hand-Foot Syndrome
03/2019 - 01/2019
2Pleural Effusion (Pleural Effusions)
01/2019 - 01/2015
2Chronic Kidney Failure (Chronic Renal Failure)
10/2017 - 04/2012
2Acute Kidney Injury (Acute Renal Failure)
07/2016 - 08/2008
2Exanthema (Rash)
06/2016 - 07/2015
2Neoplasm Metastasis (Metastasis)
01/2015 - 06/2013
2Lymphatic Metastasis
06/2014 - 06/2013
2Hyperbilirubinemia
03/2014 - 01/2014
1Treatment-Resistant Schizophrenia
10/2021
1Liver Cirrhosis (Hepatic Cirrhosis)
11/2020
1Nephrosclerosis
07/2020
1Chronic Renal Insufficiency
07/2020

Drug/Important Bio-Agent (IBA)

13Tacrolimus (Prograf)FDA LinkGeneric
11/2019 - 11/2007
11Pharmaceutical PreparationsIBA
10/2021 - 11/2010
11Cytochrome P-450 CYP3AIBA
01/2019 - 08/2008
10nilotinibFDA Link
01/2022 - 04/2012
8Tyrosine Kinase InhibitorsIBA
11/2021 - 09/2013
8Imatinib Mesylate (Gleevec)FDA Link
01/2019 - 11/2010
7Proteins (Proteins, Gene)FDA Link
01/2021 - 12/2007
7Dasatinib (BMS 354825)FDA Link
07/2020 - 04/2012
7C-Reactive ProteinIBA
01/2015 - 10/2009
6Gefitinib (Iressa)FDA Link
08/2020 - 02/2014
5Lenalidomide (CC 5013)FDA Link
05/2019 - 08/2014
5Peptides (Polypeptides)IBA
12/2014 - 12/2007
4bosutinibIBA
01/2021 - 01/2018
4DNA (Deoxyribonucleic Acid)IBA
06/2014 - 10/2010
4AnionsIBA
11/2010 - 12/2007
3lenvatinibIBA
05/2022 - 01/2019
3Dexamethasone (Maxidex)FDA LinkGeneric
05/2019 - 01/2018
3ATP-Binding Cassette Transporters (ABC Transporters)IBA
01/2019 - 11/2017
3Member 1 Subfamily B ATP Binding Cassette TransporterIBA
09/2015 - 10/2008
3Mycophenolic Acid (Cellcept)FDA LinkGeneric
01/2015 - 12/2007
3Uridine Diphosphate (UDP)IBA
03/2014 - 01/2009
3Interleukin-6 (Interleukin 6)IBA
01/2012 - 10/2009
3CytokinesIBA
07/2011 - 11/2007
3Interleukin-10 (Interleukin 10)IBA
07/2011 - 10/2009
3Interleukin-4 (Interleukin 4)IBA
07/2011 - 10/2009
3Interleukin-2 (IL2)IBA
07/2011 - 10/2009
3ATP-Binding Cassette Sub-Family B Member 4IBA
11/2010 - 10/2008
2PlatinumIBA
01/2022 - 01/2021
2Clozapine (Clozaril)FDA LinkGeneric
10/2021 - 11/2017
2ponatinibIBA
08/2021 - 01/2019
2Immunosuppressive Agents (Immunosuppressants)IBA
11/2019 - 07/2012
2Sunitinib (Sutent)FDA Link
05/2018 - 01/2017
2Cytochrome P-450 CYP2D6 (CYP2D6)IBA
11/2017 - 07/2015
2Proton Pump InhibitorsIBA
11/2017 - 04/2012
2EnzymesIBA
07/2015 - 07/2011
2Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA
03/2014 - 01/2014
2Lansoprazole (Prevacid)FDA LinkGeneric
04/2012 - 09/2010
2Triglycerides (Triacylglycerol)IBA
01/2011 - 10/2007
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2010 - 10/2009
2Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
05/2010 - 10/2009
2InterleukinsIBA
05/2010 - 10/2009
2Interferon-gamma (Interferon, gamma)IBA
11/2009 - 10/2009
1AngiopoietinsIBA
05/2022
1Fluorouracil (Carac)FDA LinkGeneric
01/2022
1Biomarkers (Surrogate Marker)IBA
11/2021
1AfatinibIBA
10/2021
1Antipsychotic Agents (Antipsychotics)IBA
10/2021
1Copper Transporter 1IBA
01/2021
1P-type ATPasesIBA
01/2021
1CreatinineIBA
01/2021
1Epidermal Growth Factor (EGF)IBA
12/2020
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
08/2020
1EverolimusFDA Link
06/2020
1regorafenibIBA
04/2020

Therapy/Procedure

15Therapeutics
05/2022 - 09/2010
8Transplantation
11/2019 - 08/2008
6Kidney Transplantation
11/2019 - 08/2008
5Renal Dialysis (Hemodialysis)
11/2020 - 04/2012
5Drug Therapy (Chemotherapy)
04/2020 - 07/2012
4Esophagectomy
07/2011 - 10/2009
2Cranial Irradiation
12/2017 - 01/2015
2Lymph Node Excision (Lymph Node Dissection)
06/2014 - 06/2013
1Neoadjuvant Therapy
01/2021
1Thrombectomy
01/2021